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Crock Pot Mississippi Pot Roast Sandwich on a white plate next to peppers
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4.95 from 20 votes

Crock Pot Mississippi Pot Roast Sandwiches

Crock Pot Mississippi Pot Roast Sandwiches are an easy and delicious slow cooker recipe that is perfect for busy weekdays or even Sunday dinner!  Slow cooked beef with spicy pepperoncini peppers and Italian seasonings, gets shredded, then topped with cheese and served on crusty rolls for an satisfying family meal.
Prep Time10 mins
Cook Time6 hrs
Total Time6 hrs 10 mins
Course: Dinner
Cuisine: American
Servings: 8 people
Calories: 589kcal
Author: Amy Nash


  • 3 lb beef chuck roast
  • 2 Tablespoons olive oil
  • freshly ground black pepper
  • 1 packet dry Italian seasoning/salad dressing mix
  • 1 packet dry au jus gravy mix
  • 10-12 pepperoncini peppers plus ½ cup juice from the jar
  • ¼ cup butter
  • 8 ciabatta rolls
  • 8 slices provolone cheese
  • butter
  • mayonnaise


  • Season the roast with pepper (no need to salt it as there will be plenty of salt in the seasoning packets already).  Heat a large skillet over medium-high heat, then add the oil.  Brown the roast on all sides in the hot oil, then transfer to a large slow cooker.  This step can be skipped, if you don't have time.
  • Dump the packets of Italian seasoning and au jus gravy mix, along with the pepperoncini peppers, ½ cup of their juice, and the butter, right on top of the roast.  Cover and cook on LOW for 8-10 hours or on HIGH for 5-6 hours, until the beef shreds easily with a fork. 
  • Once the meat is shredded, butter and toast the buns, then spread with a thin layer of mayonnaise.  Pile the shredded pot roast onto the bottom buns and top with a slice of Provolone cheese.  Toast under a broiler just until the cheese is melted, then top with the remaining buns and enjoy!


Calories: 589kcal | Carbohydrates: 27g | Protein: 43g | Fat: 34g | Saturated Fat: 16g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 15g | Trans Fat: 1g | Cholesterol: 146mg | Sodium: 746mg | Potassium: 626mg | Fiber: 1g | Sugar: 1g | Vitamin A: 411IU | Vitamin C: 10mg | Calcium: 178mg | Iron: 4mg